Usuthu are currently on a three-match unbeaten streak across all competitions.
They recently thrashed Mighty Eagles 5-1 in the Nedbank Cup, followed by an emphatic 5-1 league victory over SuperSport United. Their latest outing saw them earn a hard-fought 2-2 draw away at Kaizer Chiefs.
AmaZulu sit ninth in the league table with 20 points and will be eager to climb higher with another positive result.
In contrast, Gallants find themselves in 13th place with 15 points and are coming off a disappointing 2-1 defeat to Richards Bay.
Marumo Gallants, however, can take confidence from their last meeting with AmaZulu, having secured a victory in their previous league encounter in September.
The home side will have a full squad available, with no suspensions affecting their line-up. Gallants, on the other hand, will be without two key players.
Siyabulela Shai remains suspended as he serves the second match of his two-game ban, while Edson Khumalo will also miss out after picking up his fourth yellow card of the season against Richards Bay.
Orlando Pirates clinched the Carling Knockout Cup in dramatic fashion at the New Peter Mokaba Stadium, edging Marumo Gallants 1-0 after extra time to secure their second trophy of the season.
Marumo Gallants' goalkeeper Washington Arubi says his side is comfortable being labelled the underdogs ahead of Saturday's Carling Knockout final against Orlando Pirates.
Kaizer Chiefs co-coach Khalil Ben Youssef has admitted his side continues to struggle in front of goal but insists the team is working hard to solve the problem ahead of Sunday’s clash with TS Galaxy in Mbombela.
Orlando Pirates face Marumo Gallants in the Carling Knockout Cup final at Peter Mokaba Stadium on Saturday as they attempt to win their second trophy this season.
