Sundowns lost in the final of the Carling Knockout Cup to Magesi and in the semi-finals of the MTN8 to Stellenbosch.
They are, however, top of the Betway Premiership standings and through to the knockout rounds of the CAF Champions League as well as in the last 16 of the Nedbank Cup.
They have been playing two fixtures a week for much of the current campaign and most recently saw off title challengers Orlando Pirates 4-1.
Next up is a league clash with TS Galaxy, who are unbeaten in their last 12 fixtures, on Tuesday, ahead of a cup clash with Mpheni Home Defenders on Sunday.
Cardoso said in the Citizen: "We have a huge responsibility on the match as you might imagine after the win against Pirates, the responsibility increases. We have accumulated a good number of points after the first half of the championship but there's still the second half to play.
"I will keep saying that the championship is far away from being finished, but with each match we play, we can close it. There are a lot of games to go so we just have a small advantage that we should respect and how we respect it, it's to give our best on Tuesday. I've already told the player in the change room that we celebrate but there's no time for parties.
"They must go home and rest because there's another match and the responsibility comes from our jersey that obliges us to be on top of our performance. The past speaks for itself and we must be on the high of that past."
Cardoso added: "Look, this game for Pirates was prepared in 20 minutes on the pitch where we didn’t run but we just positioned the players. When the ball is from here to there, when we win it in different moments, what we do, video analysis and team meetings. That's how we prepare because there;s no time to train. If we train the players, they will not arrive in the match in a good condition."
Golden Arrows coach Manqoba Mngqithi has voiced concern over Mamelodi Sundowns' recruitment strategy, warning that the club's reliance on foreign signings is weakening Bafana Bafana.
Mamelodi Sundowns were held to a 1-1 draw by Siwelele in their Betway Premiership encounter at Dr Petrus Molemela Stadium on Wednesday.
Aubrey Modiba has urged Mamelodi Sundowns to remain focused on the job at hand as they prepare to face Siwelele, while attempting to catch Orlando Pirates.
Mamelodi Sundowns battled to a gritty 0-0 draw against MC Alger in a feisty CAF Champions League showdown on Friday night.
