Sundowns lost in the final of the Carling Knockout Cup to Magesi and in the semi-finals of the MTN8 to Stellenbosch.
They are, however, top of the Betway Premiership standings and through to the knockout rounds of the CAF Champions League as well as in the last 16 of the Nedbank Cup.
They have been playing two fixtures a week for much of the current campaign and most recently saw off title challengers Orlando Pirates 4-1.
Next up is a league clash with TS Galaxy, who are unbeaten in their last 12 fixtures, on Tuesday, ahead of a cup clash with Mpheni Home Defenders on Sunday.
Cardoso said in the Citizen: "We have a huge responsibility on the match as you might imagine after the win against Pirates, the responsibility increases. We have accumulated a good number of points after the first half of the championship but there's still the second half to play.
"I will keep saying that the championship is far away from being finished, but with each match we play, we can close it. There are a lot of games to go so we just have a small advantage that we should respect and how we respect it, it's to give our best on Tuesday. I've already told the player in the change room that we celebrate but there's no time for parties.
"They must go home and rest because there's another match and the responsibility comes from our jersey that obliges us to be on top of our performance. The past speaks for itself and we must be on the high of that past."
Cardoso added: "Look, this game for Pirates was prepared in 20 minutes on the pitch where we didn’t run but we just positioned the players. When the ball is from here to there, when we win it in different moments, what we do, video analysis and team meetings. That's how we prepare because there;s no time to train. If we train the players, they will not arrive in the match in a good condition."
Marumo Gallants coach Alexandre Lafitte believes his side has what it takes to pull off another upset when they face Orlando Pirates in the Carling Knockout final at Peter Mokaba Stadium on December 6.
Miguel Cardoso says Mamelodi Sundowns need to build on their 1-0 midweek win over TS Galaxy to make up for a poor start to the Betway Premiership campaign.
Mamelodi Sundowns coach Miguel Cardoso has praised Sphelele Mkhulise's influence and professionalism, describing the midfielder as a player who represents the very identity of the club.
Mamelodi Sundowns maintained their lead at the top of the Betway Premiership, while there were also wins for Siwelele FC and Durban City in Wednesday night's domestic action.
