Chacarra began the final round with a comfortable lead after a brilliant third-round 63 that put him on 19 under going into Sunday.
He never looked in serious danger of surrendering the advantage, carding a two-under-par 70 that included enough birdies to keep New Zealand's Daniel Hillier at arm's length.
Hillier, who had fought his way up the leaderboard with strong middle rounds of 64 and 64, produced the day's best score among the contenders with a five-under 67 but it was not enough as he finished two back.
Poland's Adrian Meronk and fellow Spaniard Angel Hidalgo shared third place at 15-under after final rounds of 68 and 69 respectively.
A group of players including Tommy Fleetwood, Joost Luiten, Gregorio De Leo and JC Ritchie finished tied for fifth at 13-under.
Chacarra's victory marked another strong performance on Indian soil as the Spaniard's second win in the country, and his consistency across four rounds at the Delhi Golf Club proved decisive.
He opened with consecutive 67s before the low round of the tournament on Saturday and closed the deal with a composed final day.
The $4 million DP World Tour event, jointly sanctioned with the DP World PGTI, was affected by weather delays earlier in the week, but the final round proceeded smoothly under clear conditions in New Delhi.
South African Casey Jarvis boosted his chances of challenging for the Race to Dubai title after grabbing a one-shot lead on day one of the Genesis Championship in South Korea.
Louis Oosthuizen has confirmed he will not re-sign with LIV Golf, opting to return to the DP World Tour in January 2027 in what he describes as the hardest decision of his professional career.
Spain's Eugenio Chacarra clinched a sensational two-stroke victory at the DP World India Championship on Sunday, catapulting himself to the top of the Race to Dubai standings.
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