Head coach Didier Deschamps said on Friday that his players are prepared to deal with whatever conditions they encounter, as the northeastern United States continues to endure an intense heatwave.
The match is set to begin at 5:00 pm local time (23:00 SAST), with the US National Weather Service's extreme heat warning remaining in force until Saturday evening. Philadelphia reached 38°C on Friday, while weather alerts remain active across the area.
The city will also mark the 250th anniversary of American independence on the same day the knockout encounter is staged.
France have already experienced disrupted conditions in Philadelphia during the group stage, when their 3-0 victory over Iraq was interrupted by a two-hour storm delay.
Concerns over player welfare in such conditions have previously been highlighted by global players' union FIFPro, which warned during last year's Club World Cup in the United States about the risks of competing in extreme weather.
"We knew it would be very hot. I think tomorrow it will be a little cooler than today, and I hope there are no storms this time," Deschamps told reporters.
"It is something we need to take into account, but I think every team has prepared for it. It can have an impact on all the teams.
"This will be our fifth game at the tournament and that will have an impact as well, but I am not fixated on the heat."
Deschamps has a virtually full-strength squad available, with only Marcus Thuram unavailable through injury, as France aim to continue their impressive tournament form.
Ghana coach Carlos Queiroz admitted his side failed to produce the performance they had prepared for after their 1-0 defeat to Colombia ended the Black Stars' FIFA World Cup campaign at Arrowhead Stadium in Kansas City on Saturday.
Canada coach Jesse Marsch insists there is no desire for revenge when his side face Morocco in Saturday's FIFA World Cup Round of 16 clash, despite their painful defeat to the North Africans four years ago.
New Zealand beat France 34-32 in a keenly contested Nations Championship clash in Christchurch on Saturday as Dave Rennie's tenure as head coach kicked off with a win.
England's preparations for their World Cup Round of 16 clash with tournament co-hosts Mexico have been marred by logistical uncertainty and a hostile reception.
