Siraj played 17 matches for Gujarat Titans in the IPL and was also part of India's team that beat Afghanistan by an innings and 300 runs in a one-off Test match.
"Following discussions between the BCCI Medical Team and the Team Management, Siraj has been advised a period of rest as part of his workload management programme," the BCCI said in a release.
"The decision has been taken as a precautionary measure to ensure adequate recovery ahead of a long international season."
Siraj's Gujarat Titans teammate Prasidh Krishna has been added to India's T20 squad that will two games against Ireland in Belfast later this month followed by five matches in England early next month.
Prasidh was also included in India's squad for the upcoming three-match ODI series at home against Afghanistan that starts on Saturday.
Shreyas Iyer is still looking for his first win since becoming India's T20I captain but says the challenging start will make him a better player and leader in the future.
Jos Buttler hit a swashbuckling century as England continued to dominate India, the hosts beating the visitors by 56 runs in the final game in Southampton to win the five-match T20I series 4-0.
India T20I captain Shreyas Iyer admitted his team is going through a transition period after losing to England by nine wickets to surrender the series 3-0.
England secured a series-winning nine-wicket victory in swashbuckling style against India in the fourth T20I in Bristol on Thursday.
