The Super Eagles are in third position in Group C, three points behind Benin and South Africa, needing to win both matches and hope for Bafana Bafana to lose in order to secure qualification.
"Everybody can go to the World Cup," said head coach Chelle ahead of Lesotho clash.
"This is football, anything can happen during the game because of the weather, the referee, injuries, or other factors. So, we need to stay focused on what we want from this game."
Nigeria will be boosted by the return of Galatasaray star striker Victor Osimhen who missed the 1-1 draw against South Africa last month after suffering an injury in the previous match.
“We want to have this victory, and after that, there will be another game. So, for sure, we must be 100% focused on this match tomorrow against Lesotho, a great team with a good coach,” added Chelle.
"We need to start well, with a lot of intensity and aggressiveness, to score and to win this game."
The Super Eagles will face the Crocodiles at the Peter Mokaba Stadium on Friday before hosting Benin at the Godswill Akpabio Stadium on Tuesday.
Nigeria international Samuel Chukwueze has expressed his excitement at rediscovering top form at Fulham, crediting manager Marco Silva for playing a crucial role in his resurgence.
Pico Lopes is looking forward to Cape Verde's 2026 FIFA World Cup campaign after drawing Spain, Saudi Arabia, and Uruguay in Group H.
England will head into the 2026 FIFA World Cup grouped with Croatia, Ghana and Panama, as the expanded 48-team tournament begins to take shape following Friday evening's draw.
Aleix Garcia is enjoying the best spell of his career, turning himself into a key figure in Bayer Leverkusen's midfield and pushing for a place in Spain's 2026 World Cup squad.
