With Arsenal sitting top of the table on 48 points and Liverpool in fourth with 34 after 20 games, the stakes are high for both clubs. Arsenal have won 15 and lost only two matches so far this season.
Van Dijk spoke openly about the challenge ahead after Liverpool's dramatic 2-2 draw with Fulham that extended their unbeaten run to eight games. "We all know at home they are unbeaten this season, I think, in all competitions," he said.
"It is a nice challenge and we should be ready for a big fight. I'm really looking forward to it and I think everyone should."
The Netherlands defender underlined the quality Arsenal possess both in their starting lineup and on the bench, adding that Liverpool will study their strengths carefully. "They have a fantastic squad," Van Dijk said. "There is no reason to not look forward to it. Another opportunity, but first recover and then we will focus on that."
Liverpool's head coach Arne Slot has described this season as a "constant battle", acknowledging that Liverpool are chasing rather than leading the title race, with Arsenal and Manchester City ahead. Slot has highlighted defensive improvements during Liverpool's recent run, but also admitted the side has struggled for attacking sharpness.
Both teams bring momentum into Thursday's clash. Arsenal thrashed Aston Villa 4-1 in their last outing, stretching their lead at the top of the league.
For Liverpool, Van Dijk's focus is simple: fight, take confidence from recent results and target a positive performance. "Every game in the Premier League is very difficult," he said after the Fulham draw, "but we have to keep fighting."
This showdown promises intensity and fine margins, with Van Dijk's leadership and the Reds' recent resilience set to be key factors at the Emirates.
Thomas Frank has said Tottenham's latest setback was "extremely painful" after a dramatic stoppage-time defeat at Bournemouth, as the Spurs head coach faces fresh scrutiny following a chaotic night on and off the pitch.
Arne Slot has hit back strongly at claims Liverpool have become "boring", insisting his team remain committed to attacking football as they prepare to face Premier League leaders Arsenal tonight.
Ten-man Chelsea were defeated 2-1 by Fulham in their Premier League clash at Craven Cottage on Wednesday to extend their winless run to five matches.
Manchester United's first match since Ruben Amorim's dismissal ended in frustration as relegation-threatened Burnley fought back to earn a 2-2 draw at Turf Moor.
