Scrumhalf Embrose Papier has been ruled out with a late niggle, with Paul de Wet stepping in to wear the No 9 jersey, while Zak Burger moves onto the bench.
The Bulls have named a lineup packed with Springboks as they aim to build on their recent resurgence. By contrast, the Stormers arrive in Pretoria under pressure following three consecutive defeats.
Coach Johan Ackermann, however, cautioned that form often counts for little when these traditional rivals meet.
Kick-off is scheduled for 2pm.
Bulls coach Johan Ackermann admitted his side "fell apart" in their 32-19 home defeat to the Stormers at Loftus on Saturday, leaving his team facing a high-pressure run-in for the remainder of the United Rugby Championship season.
John Dobson described the Stormers' 32-19 victory over the Bulls at Loftus Versfeld on Saturday as "probably our most important win" and one of their most dominant performances in Pretoria since he took charge.
The Stormers rediscovered some of their best form to claim a 32-19 bonus-point victory against the Bulls in their United Rugby Championship clash at Loftus on Saturday.
The Stormers welcome back three players with over 100 caps for the club in their United Rugby Championship derby against the Bulls at Loftus Versfeld on Saturday.
