The Namibian Premiership side are trailing their Betway Premiership counterparts 1-0 from the first leg held at the Botswana National Stadium last weekend.
Only a victory will see them through to the group stages and Guther insists his team are well prepared to face the might of the South African champions.
"I think it will be a great moment for everyone, and I think, like my captain said, the guys are going to be hyped for the situation, the Friday night lights. We're looking forward to it," he said on iDiski Times.
"I don't think there needs to be mental preparation. The guys know what kind of atmosphere is here in this particular stadium and for that they're prepared."
"We have to come in here with confidence. We can't walk in here and be intimidated by the opponents. We do respect them 100%, but we can't show any type of fear – they are an extremely well-organised and trained team," added the head coach.
Guther has only been i charge of African Stars for a little over a month but has high hopes of overturning their narrow deficit.
"We trained very hard and worked a lot on our play, how we'll set up, so I do fancy our chances. We just have to come out here and leave everything on the field," he said.
Orlando Pirates breezed into the CAF Champions League group stage after a dominant 4-0 victory over Namibian side African Stars at the Orlando Stadium to secure a 5-0 aggregate victory.
Mamelodi Sundowns have been eliminated from the CAF Champions League by Angolan Girabola league leaders Wiliete SC on away goals.
Golden Arrows have officially announced that Mandla Ncikazi has rejoined the club as head coach after parting ways with Pitso Dladla on Thursday evening.
Orlando Pirates head coach Abdeslam Ouaddou says that he won't rush Oswin Appollis back to competitive action.
