The experienced Solontsi co-captained the side with Unam Tose against Italy last month, with Tose named vice-captain for the two Tests, the first internationals between the two countries on South African soil.
Latsha was withdrawn from the squad on Saturday at the conclusion of their training camp in Stellenbosch, while it was also confirmed that Nombuyekezo Mdliki has failed to recover from her rib injury sustained against Spain earlier this month.
Their replacements will be confirmed on Monday.
The Springbok Women have made three changes to their starting team for Saturday's WXV Global Series Test against Ireland in Cape Town, with Yonela Ngxingolo set to earn her 50th cap.
The Irish women present an unknown factor for the Springbok Women when they clash in the WXV Global Series at Athlone Stadium in Cape Town on Saturday.
Anacadia Minnaar and Insaaf Levy have rejoined the Springbok Women's squad for their two-Test series against Ireland in Cape Town later this month.
The Springbok Women finished their WXV Global Series tour on a high with a comprehensive 20-0 victory over Spain in Seville on Sunday.
