The duo were released from the Springbok squad for the Greatest Rivalry encounter. It will be the All Blacks' final match against the South African franchises, after which they switch focus to the Tests.
Horn starts at fullback for the Lions, with wingers Kelly Mpeku and Elrich Cronje either side of him. The relentless Henco van Wyk is at outside centre, paired with Richard Kriel.
Nico Steyn and Chris Smith will control the tempo at scrumhalf and flyhalf. Captain and No.8 Franke Horn has powerhouse Batho Hlekani and the talented Siba Mahashe on his flanks, while an experienced tight five will look to do the damage up front.
Springbok loosehead prop Boan Venter is on the bench, along with former Sevens star JA Pretorius and former Junior Bok Haashim Pead.
Lions - 15 Quan Horn, 14 Kelly Mpeku, 13 Henco van Wyk, 12 Richard Kriel, 11 Erich Cronje, 10 Chris Smit, 9 Nico Steyn, 8 Francke Horn (c), 7 Batho Hlekani, 6 Siba Mahashe, 5 Ruan Delport, 4 Etienne Oosthuizen, 3 Sebastian Lombard, 2 PJ Botha, 1 SJ Kotze.
Replacements: 16 Morne Brandon, 17 Boan Venter, 18 RF Schoeman, 19 Hyron Andrews, 20 Sikhumbuzo Notshe, 21 JC Pretorius, 22 Haashim Pead, 23 Boeta Chamberlain.
Lions head coach Ivan van Rooyen admitted his side are a little undercooked for their Rugby's Greatest Rivalry tour match against the All Blacks but believes the occasion will help elevate their performance.
Springboks Pieter-Steph du Toit and Ox Nche both earn career milestones in the second Test of Rugby's Greatest Rivalry against the All Blacks in Cape Town this Saturday.
New Zealand superstar flyhalf Richie Mo'unga will make his long-awaited return to the All Blacks for their Rugby's Greatest Rivalry fixture against the Lions on Tuesday.
Springbok centre Jesse Kriel was gracious in defeat, but promised they would come back stronger after their loss at the hands of the All Blacks in Rugby's Greatest Rivalry Series opener in Johannesburg on Saturday.
