Carse trapped Karun Nair and captain Shubman Gill lbw in a crucial spell from the Pavilion End. Ben Stokes then bowled nightwatchman Akash Deep with the final ball of the day, leaving India 58-4, still 135 runs short of their target of 193.
Earlier, England were bowled out for 192 on a deteriorating pitch. Washington Sundar took 4-22, while Jasprit Bumrah claimed two wickets. England collapsed from a strong position, losing their last six wickets for 38 runs.
Harry Brook was bowled for 23 sweeping Akash Deep. Joe Root made 40 and Stokes 33, both falling to Sundar. In total, 12 England batters were bowled — a record for a home Test.
In India’s reply, Jofra Archer dismissed Yashasvi Jaiswal for a duck. Chris Woakes dropped a return catch off KL Rahul when he was on 5.
England looked to be fading before Carse’s impact and Stokes’ final strike. The match is finely balanced heading into the final day.
Shoaib Bashir, who injured his finger on day three, is available to bowl but is likely to miss the final two Tests.
Third Rothesay Test, Lord's (day four of five)
England 387 (Root 104, Carse 56, Smith 51; Bumrah 5-74) & 192 (Root 40; Sundar 4-22)
India 387 (Rahul 100, Pant 74, Jadeja 72; Woakes 3-84) & 58-4 (Rahul 33*, Carse 2-11)
India need 135 runs to win
England took the last wicket in the final session on the fifth day to seal a dramatic 22-run victory against India in the third Test at Lord's to take a 2-1 lead in the five-match series.
On a sun-soaked opening day of the third Test at Lord's, Joe Root's masterful unbeaten 99 steadied England to 251-4 against a probing Indian attack.
India captain Shubman Gill has earned high praise from cricket legend Sachin Tendulkar for both his leadership and exceptional batting during the ongoing Anderson-Tendulkar Test series.
India captain Shubman Gill continued his red-hot form with the bat to put India in command of England ahead of the final day of the second Test at Edgbaston.
