South Africa play the Red Tide as part of their preparations for the 2026 World Cup kicking off in the United States, Canada and Mexico in June.
Broos' team host Panama at the Moses Mabhida Stadium on Friday, 27 March and at the DHL Stadium on Tuesday, 31 March.
Notable admissions from Broos' squad include Orlando Pirates midfielder Sipho Mbule and Steaua Bucurest's Siyabonga Ngezana.
Orlando Pirates goalkeeper Sipho Chaine and Mamelodi Sundowns striker Iqraam Rayners were also left out but Sundowns midfielder Themba Zwane returns to the squad after missing out on the 2025 Africa Cup of Nations due to injury.
Minnesota United striker Bongokuhle Hlongwane and Sundowns forward Thapelo Maseko were also recent inclusions.
Full squad:
Goalkeepers: Ronwen Williams [Mamelodi Sundowns], Ricardo Goss [Siwelele FC], and Renaldo Leaner [Sekhukhune United].
Defenders: Nkosinathi Sibisi [Orlando Pirates], Aubrey Modiba, Khulumani Ndamane, Khuliso Mudau [all Mamelodi Sundowns], Ime Okon [Hannover 96, Germany], Samukelo Kabini [Molde FK, Germany], Mbekezeli Mbokazi [Chicago Fire FC, USA], Thabang Matuludi [Polokwane City]
Midfielders: Teboho Mokoena, Jayden Adams [all Mamelodi Sundowns], Thalente Mbatha [Orlando Pirates], Sphephelo Sithole [C.D. Tondela].
Forwards: Oswin Appollis, Tshepang Moremi, Evidence Mokgopa, Relebohile Mofokeng [all Orlando Pirates], Lyle Foster [Burnley, England], Bongokuhle Hlongwane [Minnesota United FC, USA], Themba Zwane [Mamelodi Sundowns] and Thapelo Maseko [AEL Limassol, Cyprus].