Injuries have cast a shadow over both teams. Everton will be without Dominic Calvert-Lewin, Youssef Chermiti, Armando Broja, and winger Dwight McNeil for the match.
Additionally, captain Seamus Coleman remains unavailable, while Nathan Patterson is a doubt. Orel Mangala's knee injury has ruled him out for the remainder of the season.
However, there is some positive news for Everton with left-back Vitalii Mykolenko returning to training after missing the FA Cup loss to Bournemouth.
Liverpool, too, faces its share of injury concerns, with Joe Gomez sidelined due to a recurring hamstring issue.
On a brighter note, Trent Alexander-Arnold has returned to training following a thigh injury, and Curtis Jones is fit to play.
This delayed fixture, initially postponed due to Storm Darragh in December, holds immense significance for both clubs.
Everton, now nine points clear of the relegation zone, will aim to extend their positive run under David Moyes, who has led the Blues to three wins from his first four Premier League matches in charge.
Meanwhile, Liverpool will look to widen their six-point advantage over Arsenal at the top of the table, with their game in hand on the Gunners still pending due to postponements.
Nottingham Forest are set to receive a double injury boost ahead of their Premier League showdown with champions Liverpool after the international break, with both Chris Wood and Callum Hudson-Odoi expected to return to action.
David Moyes has praised James Garner for his outstanding form this season, saying the Everton midfielder is edging closer to an England call-up.
Arne Slot believes Liverpool's toughest spell of the season is now behind them, with a crucial run of winnable fixtures offering a chance to reignite their campaign after a heavy defeat to Manchester City.
Pep Guardiola celebrated his 1000th match as a manager in fitting fashion on Sunday, guiding Manchester City to a commanding 3-0 win over Liverpool at a rain-soaked Etihad Stadium.
