After electing to bat first, England piled on a mammoth 400 for 8, ending a seven-match losing streak in ODIs and taking a 1-0 lead in the three-match series.
Making his debut as England's permanent white-ball captain, Harry Brook led from the front with a composed 58, anchoring a power-packed top order. It was Barbados-born Jacob Bethell, however, who stole the show on his Warwickshire home ground. Back from IPL duty, the 20-year-old smashed 82 off 62 balls, marking a breakout performance on the international stage.
Support came from Ben Duckett (60) and Joe Root (57), as England's top four all notched half-centuries in a batting masterclass.
For the West Indies, it was a bruising day with the ball. While Jayden Seales claimed 4 wickets, he was expensive - conceding 84 runs in nine overs - as England's batters took control from the outset.
Needing a record run chase to win - only South Africa's legendary 438-9 against Australia in 2006 surpasses the target - the West Indies crumbled under pressure.
They were bowled out for just 162 in 26.5 overs, with tailender Seales' unbeaten 29 the top score in a dismal innings that saw only three batters reach 20.
England's bowlers maintained relentless pressure. Jamie Overton (3-22) and Saqib Mahmood (3-32) led the charge, backed by sharp fielding and disciplined lines that never allowed the visitors to settle.
The emphatic result sends a strong message about England's intent in white-ball cricket under Brook's leadership, particularly after a difficult run of recent form.
The series now moves to Cardiff on Sunday before concluding at The Oval on Tuesday.
England allrounder Jamie Overton has been ruled out of the remainder of the white-ball series against West Indies after sustaining a fractured right little finger during the first ODI at Edgbaston.
Talismanic England captain Ben Stokes wants his charges to employ an ultra-positive mindset for the next cycle of the ICC World Test Championship.
Roston Chase has been appointed as West Indies' new Test captain, the allrounder taking over the reins from Kraigg Brathwaite, who resigned in March after 39 matches in charge.
Gujarat Titans batsman Jos Buttler is set to miss the rest of the IPL 2025 season following his selection for England's upcoming series against the West Indies.
