The 20-year-old was replaced by Kamogelo Sebelebele after 62 minutes in the 1-0 Carling Knockout win over Siwelele on Saturday.
Mofokeng went down with an injury and had to be stretchered off, before Bucs captain Mbekezeli Mbokazi netted an 87th minute winner.
The Pirates midfielder was selected for Bafana's upcoming World Cup qualifiers with Zimbabwe and Rwanda.
Speaking after the game, Ouaddou said it was too early to tell if Mofokeng will be ruled out.
He said on SuperSport: "To be honest, for now, we just finished the game, I cannot tell you anything about Rele – I think he played one hour and did well.
"I'm happy with what he did, we will see the issue, we will see if he is okay or not [for Bafana Bafana] but for me, he played one hour – I don't have much to say about that."
Marumo Gallants coach Alexandre Lafitte believes his side has what it takes to pull off another upset when they face Orlando Pirates in the Carling Knockout final at Peter Mokaba Stadium on December 6.
Orlando Pirates will enjoy home advantage when they take on Marumo Gallants in the 2025 Carling Knockout Cup final, after the Premier Soccer League (PSL) confirmed the venue and date for the much-anticipated clash.
Orlando Pirates head coach Abdeslam Ouaddou was proud to see his side secure their place in the final of the Carling Knockout with a hard-fought 1-0 win over Richards Bay on Saturday.
Orlando Pirates secured their place in a second cup final this season after edging Richards Bay FC 1-0 in the Carling Knockout semi-final at the Moses Mabhida Stadium on Saturday.
