The 20-year-old was replaced by Kamogelo Sebelebele after 62 minutes in the 1-0 Carling Knockout win over Siwelele on Saturday.
Mofokeng went down with an injury and had to be stretchered off, before Bucs captain Mbekezeli Mbokazi netted an 87th minute winner.
The Pirates midfielder was selected for Bafana's upcoming World Cup qualifiers with Zimbabwe and Rwanda.
Speaking after the game, Ouaddou said it was too early to tell if Mofokeng will be ruled out.
He said on SuperSport: "To be honest, for now, we just finished the game, I cannot tell you anything about Rele – I think he played one hour and did well.
"I'm happy with what he did, we will see the issue, we will see if he is okay or not [for Bafana Bafana] but for me, he played one hour – I don't have much to say about that."
Kaizer Chiefs goalkeeper Brandon Petersen has thrown his name firmly into the Bafana Bafana selection conversation following another Man of the Match performance in Amakhosi's 1-0 win over AmaZulu in Durban.
Abdeslam Ouaddou has expressed his disappointment after Orlando Pirates failed to secure the Betway Premiership title, following their goalless draw with Durban City on Saturday.
Orlando Pirates missed the chance to clinch the Betway Premiership title on Saturday after being held to a tense 0-0 draw by Durban City at Orlando Amstel Arena.
Bafana Bafana will officially announce their final squad for the 2026 FIFA World Cup on May 27 at the Union Buildings in Pretoria, according to South African Football Association (SAFA) president Danny Jordaan.
