The 19-year-old Republic of Ireland international departs the Amex Stadium after making 80 appearances for the Seagulls, scoring 17 goals. Ferguson spent the second half of last season on loan at West Ham United but struggled for consistent game time due to recurring injury setbacks.
Brighton head coach Fabian Hurzeler believes the move to Rome presents a fresh opportunity for the highly rated forward to rediscover form and fitness.
"Evan had a challenging period across the past season and a half, and it has been one disrupted by niggling injury issues, which hasn't allowed him a run of games," Hurzeler said.
"He is over those injuries and has come back in great shape. Now he really wants to play regularly. This is an exciting opportunity in a strong league and with the prospect of European football."
Hurzeler confirmed that the club will be monitoring Ferguson's progress closely during his time in Italy.
"We wish Evan well for the season ahead and will be watching his progress closely throughout the season," he added.
Ferguson will now look to make an impact in Serie A as he aims to reignite his development at one of Italy's most storied clubs - and potentially earn a permanent move to the Stadio Olimpico.
Marcus Rashford has completed a season-long loan move to Barcelona from Manchester United, marking a major development in the England forward's career following a turbulent period at Old Trafford.
Liverpool have completed the signing of French striker Hugo Ekitike from Eintracht Frankfurt in a deal worth up to 79 million pounds.
Brentford forward Yoane Wissa has left the club's pre-season training camp in Portugal and returned to London amid growing uncertainty over his future at the club.
Alvaro Morata, the seasoned Spanish striker, is poised for a dramatic return to Serie A with Como, as his former teammate Cesc Fabregas aims to spark a career revival ahead of the 2026 World Cup.
