According to All Nigeria Soccer, the Nigerian centre-back was back on the training pitch at the club's Cottingham base this week, easing fears over his availability following his withdrawal from international duty.
Ajayi had been forced to leave the Super Eagles camp before their friendly against Jordan due to a fitness issue, raising doubts about his readiness for club commitments.
His absence was felt during Nigeria's 2-2 draw with Jordan in Antalya, although he had already played a role earlier in the international window, featuring for 45 minutes in a 2-1 win over Iran.
The decision to pull out of the second fixture now appears precautionary, with the defender showing no lasting effects as he reintegrates with his club teammates.
Ajayi's return comes at a crucial stage of the season, as Hull City continue their push in the Championship. Having joined the Tigers as a free agent from West Bromwich Albion last summer, the 30-year-old has brought valuable experience and composure to the backline.
According to reports, Ajayi trained fully on Tuesday and is expected to be included in the travelling squad set to make the trip to Oxfordshire ahead of Friday's encounter at the Kassam Stadium.
His availability will be a welcome boost for the coaching staff, who have had to manage squad fitness carefully following the international break. With fixtures coming thick and fast, having key players back in contention could prove vital in maintaining consistency.
Should he be passed fit, Ajayi will be in line to feature against Oxford United as Hull look to build momentum and strengthen their position in the standings.
Atletico Madrid's careful management of Ademola Lookman has come into focus following reports of concern over how the forward was utilised during Nigeria's recent international friendlies.
Hamburg winger Philip Otele has expressed his joy after making his international debut for Nigeria in the 2-2 draw against Jordan on Tuesday evening.
Highly-rated Crystal Palace forward Benjamin Casey will require clearance from FIFA if he hopes to represent Nigeria in the future, following his competitive debut for England at youth level.
Chibuike Nwaiwu has opened up on an unforgettable week that saw him go from a late call-up to making his Super Eagles debut in Nigeria's 2-1 win over the Iran national football team.
