Sudanese outfit Al Hilal complete Group C but all eyes will be on Mokwena when he faces his former club with his Algeria team.
Lupopo knocked out the Buccaneers on penalties in the preliminary round after a thrilling 6-6 draw over two legs and will now return to South Africa during the group stage.
Pirates' elimination means Sundowns will be the only South African side in the continent's biggest club tournament this season.
The top two sides in each of the four groups will progress to the quarter-finals.
Defending champions from Egypt, Pyramids FC, were drawn in Group A alongside RS Berkane, Rivers United and Power Dynamos.
TS Galaxy defender Khulumani Ndamane has reportedly caught the attention of Premier Soccer League champions Mamelodi Sundowns, following his impressive displays in the current campaign.
Mamelodi Sundowns head coach Miguel Cardoso has slammed suggestions he didn't go all out for a win against Orlando Pirates in the Betway Premiership on Saturday.
A stunning strike from Orlando Pirates graduate Camren Dansin ensured the Buccaneers walked away with a valuable point in a tightly contested Betway Premiership clash against Mamelodi Sundowns.
Orlando Pirates assistant coach Mandla Ncikazi has urged the Soweto giants to focus on their own performance ahead of the Betway Premiership clash against Mamelodi Sundowns on Saturday.
