The 26-year-old former SuperSport United midfielder is reportedly eager to move for more game-time.
He played just 22 times for the Brazilians last season and is yet to feature in the current campaign.
Sekhukhune United are a reported destination for Mbule, with the player's agent Mike Makaab working hard to secure a deal.
He told FARPost: "We are seriously looking to get a loan move for Sipho Mbule in the current transfer window to get some playing minutes."
It remains to be seen if Sundowns will allow the player to leave, with head coach Manqoba Mngqithi telling iDiski Times: "I think he has been training very well, but he still has issues, because he's coming from an injury, but he's already in full training.
"He's a very good player. His quality is second to none.
“However, there are some areas of his of his football that must improve, but he's a very is a very good football player and we are happy to have him around.”
Golden Arrows and Stellenbosch FC played out a 1-1 draw at King Goodwill Zwelithini Stadium in Durban on Wednesday, in a Betway Premiership match that had crucial implications for the battle for a top-eight finish.
Mamelodi Sundowns coach Miguel Cardoso has warned his side against getting too comfortable at the top of the Betway Premiership standings.
Chippa United coach Vusumuzi Vilakazi admits his players need to improve their mental strength if they are to survive relegation from the Betway Premiership this season.
Mamelodi Sundowns moved two points clear at the top of the Betway Premiership standings after beating Marumo Gallants 3-1 at Loftus on Tuesday.
