Amakhosi currently lie in fourth spot on the league table after breaking a four-match winless run in the 1-0 victory against Durban City last Friday.
Meanwhile, top-flight newcomers Orbit College seem to have turned a corner following a tough start to the season and have won their last two matches against Richards Bay and Magesi to move away from the relegation zone.
Chiefs are set to be without key Angolan defender Inacio Miguel for the clash due to picking up a fourth yellow card against Durban City with the majority of the squad fit for action.
The Glamour Boys have been unpredictable this season but have still managed to rake up the most clean sheets in the league (7) whilst struggling to convert regularly in the final third despite new reinforcements.
"I think that was our problem last season," said coach Khalil Ben Youssef after the win against City.
"We were inconsistent in our performance and results, the target of the team for this season always is to try keep our players ready for every game.
"They have to fight for every game; we need to keep our consistency in performance and result. Like I said every game we take it as a cup. We need to win the next game to stay in the top three or the top two of the PSL."
The visiting Mswenko Boys will be hoping for more inspired performances from on-loan talisman Monnapule Saleng, who has walked away with back-to-back Man of the Match awards in the last two games.
Chiefs also their own in-form star in Sibongiseni Mthethwa who has picked up four Man of the Match awards this 2025/26 season and has helped the team remain defensively stable at the back.
A win or draw for Orbit could see them jump above Marumo Gallants in ninth spot on the table if other results favour them elsewhere
Kick-off is at 19h30.
Kaizer Chiefs will face two Egyptian teams in the group stages of the CAF Confederation Cup while Stellenbosch also learned who their opponents will be after the draw was conducted on Monday.
Kaizer Chiefs are set to welcome back two key defenders, Rushwin Dortley and Given Msimango, in what could be a timely boost for the Soweto giants' backline.
Orlando Pirates youngster Cemran Dansin has expressed gratitude to his coaches and teammates after scoring a spectacular equaliser in the 1-1 draw with Mamelodi Sundowns in the Betway Premiership.
Kaizer Chiefs forward Wandile Duba is refusing to let a lack of playing time derail his ambitions, despite facing one of the most competitive attacking line-ups in the Premier Soccer League this season.
