The defending league champions put on a solid display at Loftus Versfeld Stadium on Sunday as they edge closer towards their ninth consecutive title.
Iqraam Rayners opened the scoring for the Tshwane giants in the 32nd minute with a good header following a cross from Teboho Mokoena.
The home side looked more threatening in the second half with Tashreeq Matthews coming close from a Marcelo Allende corner before extending the lead with a neat finish in the 56th minute.
The visitors were then handed a lifeline in the 63rd minute when Aubrey Modiba handled in the box, however Puleng Marema missed the resultant penalty.
Masandawana continued to pile on the pressure as they looked for more goals and were finally rewarded five minutes from time through a Nuno Santos finish.
The sees Sundowns move five points clear of second placed Orlando Pirates, who have a game in hand, while City remain sixth.
Polokwane City head coach Phuti Mohafe has taken a firm stance on accountability, making an example of Puleng Marema after the veteran striker's costly penalty miss against Mamelodi Sundowns on Sunday.
The battle for survival in the Betway Premiership continues, while the race for a Top8-finish also intensifies in these three fixtures scheduled for Tuesday.
Polokwane City head coach Phuti Mohafe believes lapses in concentration and rushed decisions ultimately cost his side in their heavy defeat to Mamelodi Sundowns on Sunday.
Mamelodi Sundowns head coach Miguel Cardoso was full of praise for Teboho Mokoena following his standout man-of-the-match display in their victory over Polokwane City at Loftus Versfeld Stadium on Sunday.
